Main information
Name
Recombinant Human Phosphatidylinositol 4-Kinase β/PI4KB Protein(C-6His)
Price
267 EUR
Size
10µg
Catalog number
PKSH032015-10µg
More detailed information
Group
recombinants
Source
Recombinants or rec. proteins
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Background
Phosphatidylinositol 4-Kinase β (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
Formulation
Supplied as a 0.2 μm filtered solution of 25mM TrisHCl,100mM glycine,10%glycerol,pH7.3.
AP Mol Mass
95 kDa
Mol Mass
90.8 kDa
Stability and Storage
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
Endotoxin
＜1.0 EU per µg as determined by LAL test.
Purity
＞95% as determined by reducing SDS-PAGE.
Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Expressed Host
Human cells
Accession
Q9UBF8-2
Fusion tag
C-6His
Sequence
Met1-Met801
Activity
NA
Synonym
Phosphatidylinositol 4-Kinase Beta; PI4K-Beta; PI4KBeta; PtdIns 4-Kinase Beta; NPIK; PI4K92; PI4KB; PIK4CB
Phosphatidylinositol
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