anti-PICALM Antibody
180 EUR
0.02 mg, 0.1 mg
5553
anticorps
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Q13492
Homo sapiens
phosphatidylinositol binding clathrin assembly protein
PICALM
8301
1 mg/mL
in solution
NP_009097
56788366
Human, Mouse, Rat
PICALM antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PICALM Antibody is supplied in PBS containing 0.02% sodium azide.
PICALM antibody can be used for detection of PICALM by Western blot at 1 ug/mL. For immunofluorescence start at 20 ug/mL.
ELISA, Western Blot, immuno fluorescence
PICALM antibody was made against a 15 amino acid synthetic peptide from near the amino terminus of human PICALM.
IgG
Polyclonal
Rabbit
PICALM Antibody is affinity chromatography purified via peptide column.
unlabelled serum
PICALM Antibody: LAP, CALM, CLTH, Phosphatidylinositol-binding clathrin assembly protein, Clathrin assembly lymphoid myeloid leukemia protein
PICALM Antibody: PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).